Highlights • Clean, modern and intuitive interface with programmable action buttons • One-click image acquisition with automated contrast enhancement and selection of best focus plane • Extremely fast tools for separating attaching chromosomes, overlaps, and chromosome clusters • Unlimited undo functionality and access to the original image at any time • Two-click assignment of chromosomes (no drag and drop), helping to prevent hand cramps • Support of any species thanks to karyoform editor • Integrated case datasheet with direct link to the Neon database. The Fast and Convenient Routine Karyotyping System The flexible system architecture of and Ikaros simplifies the adaptation of karyotyping workstations to any workflow.

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Ikaros is network-ready and comes as a complete stand-alone system, or as a dedicated workstation either for capturing, analysis, review, or for database maintenance. Ikaros is renowned for its ease of use, flexibility and power. The main reason for its outstanding performance is a remarkable collection of intelligent features, which make it the safest and best system of its kind. The system combines an intuitive graphic user interface with a variety of powerful tools to provide the flexibility required analyzing even the most complex metaphases. Designed to minimize the number of interactions, Ikaros ensures amazingly fast results, and it is recognized as the fastest system of its kind. The flexible system architecture of all MetaSystems products simplifies the integration of Ikaros workstations in any given workflow.

The unique configuration management allows user specific individualization in terms of style and function. In complex network installations, global settings can be administered by a Neon supervisor account and are globalized with just one mouse click. The software supports many different banding techniques and resolutions. Numerous pre-defined karyogram and idiogram forms for human, animal, and plant chromosomes are available. The possibility to create individual templates with the integrated karyogram form editor makes Ikaros applicable to many different fields of research. The possibility to run chromosome comparisons by chromosome classes or by karyograms facilitates the on-screen analysis of chromosome.

Aberrant chromosomes can be easily illustrated with the ‘Cut and Join’ function for idiograms. Original images are stored as they have been captured – there is no need to keep different copies of the same image.

Any change of case and image data is automatically recorded by Neon. This guarantees a perfect audit trail of all activities, but it also allows going back to the original image or to intermediate processing stages at any time.

Thus, there are no irrecoverable mistakes: every single step towards the final result is traceable and, if required, reversible. Preparing a karyogram with Ikaros is extremely easy. On chromosome separation, object contours are shown in different colors to facilitate distinction between separated and adjacent chromosomes. Clusters of chromosomes are separated with a convenient paintbrush function, and separated chromosomes are display lined up to identify and separate remaining touching and overlapping chromosomes. Automatic chromosome classification based on user-trainable banding classifiers let the assignment of chromosomes to classes be a matter of a few seconds.

Ikaros is available in various configurations. Each single configuration can be used as a building block to compose an optimally configured multi-user environment.

Please ask MetaSystems or your local MetaSystems representative for recommendations on the best configuration for your requirements.